The plot centers on a high school in Turin, the Liceo Scientifico Caravaggio, and particularly on a freshman class and a senior class. Most teachers in the show are seen as very human and not just condemning the students who do not study enough, while some of them are the usual strict or heartless teachers. The leading character of the series is Isa Passamaglia (portrayed by Littizzetto), a teacher of Latin and Italian at the Caravaggio High and a single mother of a teenage son, who constantly bears a grudge against her. The show also deals with the personal hardships faced by Passamaglia's colleagues as well as by her students.

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