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• 
  Stan Lee
  Frank Elson
• 
  Neil Patrick Harris
  Peter Parker
• 
  Lisa Loeb
  Mary Jane Watson
• 
  Ian Ziering
  Harry Osborn
• 
  SuChin Pak
  Alison Tomita
• 
  Angelle Brooks
  Indira 'Indy' Daimonji
• 
  Keith Carradine
  J. Jonah Jameson
• 
  Edward Asner
  Officer Barr
• 
  Rino Romano
  Muang
• 
  Ethan Embry
  Max Dillon
• 
  Julie Nathanson
  Sally Johnson
• 
  Cree Summer
  Professor Williams
• 
  Jennifer Hale
  Female News Announcer
• 
  Virginia Madsen
  Silver Sable
• 
  Michael Dorn
  Kraven the Hunter
• 
  James Marsters
  Sergei
• 
  Kathy Griffin
  Roxanne Gaines
• 
  Keith David
  Agent Mosely
• 
  Karen Maruyama
  Flower Vendor
• 
  Gina Gershon
  Shikata
• 
  Clancy Brown
  Policeman
• 
  John C. McGinley
  Richard Damien
• 
  Jeremy Piven
  Roland Gaines
• 
  Jeffrey Combs
  Dr. Zellner
• 
  Xander Berkeley
  Mayor
• 
  Susan Blu
  CEO
• 
  Michael Clarke Duncan
  The Kingpin
• 
  Eve
  Cheyenne
• 
  Jeff Fischer
  Doug Reisman
• 
  Jamie Hanes
  Special Agent Roberts
• 
  Brendan Connolly
  Aleksei
• 
  Ken Lerner
  Boris
• 
  Keith Szarabajka
  Kingpin's Henchman
• 
  David Newsom
  Gary
• 
  Alexander Polinsky
  Teen #1
• 
  Tara Strong
  Christina
• 
  Harold Perrineau
  Louis Wyler
• 
  Devon Sawa
  Flash Thompson
• 
  Jane Lynch
  Oscorp Executive
• 
  Kevin Michael Richardson
  Security Guard

• Audu Paden
• Alan Caldwell
• Vincent Edwards
• Tim Eldred
• Brandon Vietti
• Sebastian Brodin
• Patrick Carroll
• Johnny Darrell
• Sean Frewer
• Ezekiel Norton
• James Taylor

• Steve Ditko
  ...
  (creator)
• Morgan Gendel
  ...
  (writer)
• Marsha F. Griffin
• Rick Suvalle
  ...
  (writer)
• Brian Michael Bendis
  ...
  (story by)
• Todd Felderstein
  ...
  (writer)
• Tracey Forbes
  ...
  (writer)
• Greg Johnson
• Steven Kriozere
  ...
  (writer)
• Scott Lipsey
• Whip Lipsey
• Stan Lee
  ...
  (characters)