Glumac:
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1. Očajnički tražeći Susan (1985), film...Susan
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2. Vision Quest (1985), film...Singer at Club
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3. Šangajsko iznenađenje (1986), film...Gloria Tatlock
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4. Tko je ta djevojka? (1987), film...Nikki Finn
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5. Dick Tracy (1990), film...Breathless Mahoney
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6. Manhattanski krimić (1991), film...Marie
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7. Madonna: Truth Or Dare (1991), film...Herself
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8. Njihova liga (1992), film...Mae Mordabito - Center Fielder
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9. Njeno tijelo je dokaz (1992), film...Rebecca Carlson
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10. Opasne igre (1993), film...Sarah Jennings
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11. Četiri sobe (1995), film...Elspeth
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12. Dim u lice (1995), film...Singing Telegram
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13. Evita (1996), film...Eva Perón
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14. Girl 6 (1996), film...Boss #3
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15. Corazón (1997), serija...Self - Presenter
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16. Neka druga ljubav (2000), film...Abbie Reynolds
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17. Valovi sudbine (2002), film...Amber
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18. Queens of Disco (2007), film...Self
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19. The Universe of Keith Haring (2008), film
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...Self
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21. Sings Bond (2012), film...Self - Presenter
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22. Madonna: Goddess of Pop (2012), film...Self (archive footage)
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23. Madonna: The MDNA Tour (2013), film...Herself - Guitar and Vocals
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24. Pussy Riot: Punk molitva (2013), film...Self (archive footage)
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25. Ko je prokleti Artur Fogel? (2013), film...Self / Singer
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26. Rok legende (2013), serija...Self
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27. Madonna: Turneja Rebel Heart (2016), film...Self - Guitar, Ukulele & Vocals
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28. Stric Howard (2016), film...Self (archive footage)
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29. Zauzmi pozu (2016), film...Self (archive footage)
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30. Avicii: Istinite priče (2017), film...Self / Singer
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...Herself
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32. Matangi/Maya/M. I. A. (2018), film...Self (archive footage)
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33. Madonna and the Breakfast Club (2019), film
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34. Keith Haring: Street Art Boy (2020), film...Self
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35. Beastie Boys Story (2020), film...Self (archive footage)
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36. 2021 MTV Video Music Awards (2021), film...Self - Presenter
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...Self (archive footage)
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38. Jagged (2021), film...Self (archive footage)
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39. Madonna - Madame X (2021), film...Self
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...Self
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41. Jean-Michel Basquiat, a Remix (2022), film...Self (archive footage)
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...Self (archive footage)
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43. George Michael Freedom Uncut (2022), film...Self
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44. Lil Nas X: Long Live Montero (2023), film...Self
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...Self
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46. The 65th Annual Grammy Awards (2023), serija...Self - Presenter
Redatelj:
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1. Prljavština i mudrost (2008), film
Scenarist:
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1. Prljavština i mudrost (2008), film
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2. Ja sam jer smo mi (2008), film
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4. Madonna: Turneja Rebel Heart (2016), film...(created by)
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5. Madonna - Madame X (2021), film...(written by)
Producent:
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1. Agent Cody Banks (2003), film...executive producer
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...executive producer
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3. Prljavština i mudrost (2008), film...executive producer
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5. Madonna: Turneja Rebel Heart (2016), film
Glas:
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1. Arthur u zemlji Minimoya (2006), film...Princess Selenia