DARSTELLER
- Mark Rylance
Leonard - Che Cartwright
Salai - Sherwin Nuland
Self - Professor of Clinical Surgery - Evelyn Welch
Self - Sussex University - Leo Stevenson
Self - Artist & Historian of Forgery - Jerry Brotton
Self - Cultural Historian - Rona Goffen
Self - Art Historian - Alan Yentob
Self - Narrator - James Frain
Cesare Borgia - James Faulkner
Sforza - Adam Croasdell
Michelangelo - Paul Brooke
Abbot - Dolya Gavanski
Mona Lisa - Christopher Benjamin
The Pope - Kai Portman
Giovanni - Martin Kemp
Self - Donald Sassoon
Self - Author 'Mona Lisa' - Simon Sanderson
Self - Scott Cassell
Self - Diver - Cherry Lewis
Self - Geologist - Mark Rosheim
Self - Gareth Padfield
Self - Robbie Whittall
Self - Adrian Nicholas
Self - Nick Avis
Self - Cardiff University - Ted Rusoff
The Astrologer - Alessandro Dieli
Father of Leonardo - Marc Nielsen
Vincenzo Peruggio