In the year 2043, scavenger James Cole (Aaron Stanford) has been recruited by a team of "Project Splinter" scientists led by physicist Katarina Jones (Barbara Sukowa), to travel back in time to the year 2015, and stop the release of a deadly virus by the enigmatic organization known as the "Army of the 12 Monkeys". In Cole's original time-line, the virus caused a plague that resulted in the death of seven billion humans in the year 2017, and its on-going mutations will mean the eventual end of the human race. In the 2015 time-line, Cole will meet and enlist the help of brilliant virologist Dr. Cassandra "Cassie" Railly (Amanda Schull); the two are brought together because a recording mentioning Cole, that Cassie made after the viral outbreak, is uncovered by Jones in the future time-line, prompting her to select Cole for the mission. Cole will also encounter a seemingly unstable math genius named Jennifer Goines (Emily Hampshire), whose father Cole has been tasked to kill, Cassie's ...
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