Acteur:
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1. Premium Blend (1997), série...Herself - Host
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2. La famille Foldingue (2000), film...Chantal
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3. Larry et son nombril (2000), série...Wanda Sykes
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4. Les pieds sur terre (2001), film...Wanda
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5. Pootie Tang (2001), film...Biggie Shorty
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6. Ellen: The Ellen DeGeneres Show (2003), série...Self - Guest
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7. Da Boom Crew (2004), série...Special Guest Voice
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8. Sa mère ou moi! (2005), film...Ruby
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9. Ma super ex (2006), film...Carla Dunkirk
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10. La ferme en folie (2006), film...Bessy the Cow (voice)
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11. Commis en folie II (2006), film...Wife
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12. Frère des ours 2 (2006), film...Innoko (voice)
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13. Old Christine (2006), série...Barb Baran
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14. Evan tout-puissant (2007), film...Rita
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15. Wanda Sykes: I'ma Be Me (2009), film...Herself
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16. Rio (2011), film...Chloe (The Goose) (voice)
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17. The Out List (2013), film...Herself
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18. Les Lionnes (2013), film...Florine Clarkston
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19. Broad City (2014), série...Dara
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20. Black-ish (2014), série...Daphne Lido
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21. Mères indignes (2016), film...Dr. Karl
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22. Chelsea (2016), série
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23. Bad Moms 2 (2017), film...Dr. Karl
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24. Larguées (2017), film...Ruth
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25. Vampirina (2017), série...Gregoria
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26. Talk Show the Game Show (2017), série...Self - Contestant
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27. Cultureshock (2018), série...Self
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29. L'année des mariages (2019), film...Janet / Grandma
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30. Jexi (2019), film...Denice
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31. Wanda Sykes: Not Normal (2019), film...Self
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32. The Other Two (2019), série...Shuli Kucerac
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33. The Bravest Knight (2019), série...Mona the Mayor
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35. Friendsgiving (2020), film...Fairy Gay Mother #2
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36. Visible : Out on Television (2020), série
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37. Breaking News in Yuba County (2021), film...Rita
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38. Tiger (2021), série...Self - Comedian
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39. La Famille Upshaw (2021), série
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40. Queer Force (2021), série
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41. Gutsy (2022), série...Self
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42. Stand Out: An LGBTQ+ Celebration (2022), film
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43. Wanda Sykes: I'm an Entertainer (2023), film...Self
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44. The Improv: 60 and Still Standing (2023), film...Self (archive footage)
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45. Albert Brooks: Defending My Life (2023), film...Self
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46. History of the World Part II (2023), série...Shirley Chisholm
Scénario:
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1. Wanda Sykes: I'ma Be Me (2009), film
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2. Wanda Sykes: Not Normal (2019), film
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3. History of the World Part II (2023), série...(writer)
Producteur:
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...executive producer
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2. Wanda Sykes: Not Normal (2019), film...executive producer
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...executive producer
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...executive producer
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...executive producer
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...executive producer
Voix:
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1. Nos voisins, les hommes (2006), film...Stella
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2. La ferme en folie (2006), film...Bessy the Cow
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3. Frère des ours 2 (2006), film...Innoko
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4. Hammy's Boomerang Adventure (2006), film...Stella
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5. Les Aventures de Frère Lapin (2006), film...Sister Moon
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6. Rio (2011), film...Chloe (The Goose)
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...Granny
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8. UglyDolls (2019), film...Wage
Réalisateur:
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1. La Famille Upshaw (2021), série