Two men, Arlo (Cuba Gooding, Jr.) a disgrunted ice cream truck driver, and Tim (Skeet Ulrich), a convenience store clerk, are forced to team up when they find themselves in possession of a top-secret bio-warfare weapon. The weapon detonates with enormous force when heated to only 50 F (10 C). The duo are up against a disillusioned former U.S. Army officer who believes he has been unjustly imprisoned as a scapegoat, and his team. He wants to obtain the weapon in order to sell it to foreign interests thus having his revenge against the government for covering up its existence and making him a scapegoat years earlier for their handling of the weapon. With time running out, and the temperature rising, Arlo and Tim must outwit their pursuers and try to find a way to dispose of the weapon before they are both killed.